This probably seems a bit of a cop out, but I think there’s room for both.
A lot of people (my partner included) would be unlikely to venture out for a 2 hour walk for 1 cache (for example). It seems inefficient if you’re a numbers person, which to an extent I think a majority of cachers are.
I would certainly be drawn to a remote cache if it’s particularly interesting (i.e. a 5/5 or similar), but if after a long hard hike it was just a tupperware tub under a rock on the floor, I’d probably find myself a bit disappointed.
A good compromise would be a remote series, or even one that starts at a road and leads you out into the wilderness. I don’t see how that would be any less rewarding…in fact by most definitions it would be more rewarding.